the situation is not adverse in war, being defeated

to run out of luck

a plan to go awry

be damned by (one's) sinful conduct

(of a disease) be severe

be displeased

the face to be soured, to be displeased, to have the taste blunted or depraved, to have a bad taste in the mouth

condition of wound to deteriorate, the condition of a wound getting bad rather than curing

glower, scowl, mood or expression to sour, look angry

become unlucky

the defluxion from the head to be suddenly stopped, the rheum to become thick and clotted

to become unidiomatic, (of someone) be using foul language

be spoiled in cooking

be corrupted or poisoned, get a bad name

be discoloured or stained, change in state or condition

feel sick

go mad